The most powerful non-surgical facelift available. Immediate, visible results. No surgery, no general anaesthetic, back to normal within 48 hours.
Immediate, visible lift the moment the threads are placed — no surgery, no scarring
Performed personally by Dr Nish Shah MD — the doctor who trains other doctors
Intraline 720 Dimension COG threads — 4× the lift force of older 360-helical threads
Results lasting 12–18 months, improving over weeks as collagen builds
Back to normal life within 24–48 hours — minimal downtime
Complimentary 4-week review included with every treatment
Dr Nish Shah MD Medical Director
PDO Thread Lift Expert · Mayfair Non-Surgical Facelift · Mayfair & Marylebone, London
Brand Ambassador & KOL — Intraline
Exclusive access to 720 Dimension COG Threads — 4× stronger than standard
Every treatment performed personally by Dr Nish
Never delegated
Senior International Clinical Trainer — Derma Medical
UK’s No.1 Aesthetics Academy · Dr Nish trains other doctors to perform this procedure
Location
58 South Molton Street, Mayfair W1K 5SL · 3 min from Bond Street
PDO Thread Lift
Before & After Results
Every result below was achieved at Medisha Clinic by Dr Nish Shah using Intraline 720 Dimension COG threads. Results are individual and may vary.
*Individual results may vary. All treatments performed by Dr Nish Shah MD at Medisha Clinic, Mayfair, London.
Treatment time
Starting price
Results duration
Downtime
Visible lift
4 week review
The Procedure
What Is a PDO Thread Lift?
PDO stands for Polydioxanone — a biodegradable synthetic polymer with a 30-year safety record in surgical medicine, trusted in cardiovascular and orthopaedic sutures for decades. In aesthetic medicine, PDO threads have been engineered to physically lift sagging facial tissue without surgery, general anaesthetic, or significant downtime.
The threads used at Medisha Clinic are COG threads — the most advanced type. Unlike basic mono or smooth threads, COG threads carry precision-engineered barbs along their length. Once inserted, these barbs anchor into the underlying soft tissue and create an immediate, mechanical lift — the same moment the needle is withdrawn, the face is lifted. As the threads dissolve naturally over 6–9 months, they trigger a sustained collagen and elastin response, meaning your skin continues to tighten and improve long after the threads have gone.
The result: an immediate, visible rejuvenation on the day, that continues to improve over the following weeks, and lasts 12–18 months — with zero scarring and a return to normal life within 48 hours.
The Technology
Why Intraline 720 Dimension Threads — And Why It Matters
Not all PDO threads are equal. The thread technology determines the strength of the lift, how long it lasts, and the collagen response. At Medisha Clinic, Dr Nish uses the Intraline 720 Dimension COG Threads exclusively.
- 4× stronger than standard threads. Clinically proven to provide four times the mechanical lift force of older 360-helical threads.
- Multi-directional barb architecture. 720 degrees of barb coverage — anchoring from every angle for a stronger hold and more natural result.
- Superior collagen stimulation. Greater barb surface area amplifies the body’s collagen response for long-term skin quality improvement.
- Results lasting 12–18 months. Superior thread strength and collagen response means patients at Medisha consistently achieve results at the upper end of the longevity range.
- Available only through certified Intraline practitioners. Dr Nish’s status as Intraline Brand Ambassador and KOL gives Medisha Clinic privileged access — unavailable at most London clinics.
720 Dimension COG vs Standard PDO Threads
Intraline 720 Dimension COG
Used exclusively at Medisha Clinic
Standard PDO Threads
Used at most other clinics
Thread Technology Compared
Thread Lift Types Compared Mono vs 360 Cog vs 720 Dimension vs PLLA Cone Threads
When patients compare thread lift brands, they are really comparing four underlying technologies. Understanding the difference matters more than any brand name — because the thread design determines the strength of the lift, how natural it looks, and how long it lasts.
Smooth Mono Threads (PDO)
- No barbs - smooth PDO filaments
- Skin rejuvenation & collagen boost
- Do not physically lift tissue
- Dissolve in around 6 months
- Best as a skin-quality add-on, not a facelift
Older 360 Cog Threads (PDO)
- Barbed lifting threads — previous generation
- Barbs arranged in a single helical plane
- Fewer anchoring points - lift tension concentrated on less tissue
- Weaker hold than modern dual-plane threads
- Still the standard thread at many London clinics
★ Intraline 720 Dimension COG — At Medisha
- Dual-plane 720° barb architecture
- 4× the mechanical lift force of older 360-helical threads
- More anchoring points — stronger, more even, more natural lift
- Results lasting 12–18 months
- Placed by the Intraline Brand Ambassador himself
PLLA Cone Threads
- Different material — poly-L-lactic acid with cones, not barbs
- Gradual collagen-led volumising effect
- Softer initial lift than barbed PDO cogs
- Material resorbs more slowly than PDO
- Suits gradual-volume goals more than a defined lift
In short: mono threads rejuvenate but do not lift; older 360 cog threads lift but are outclassed by modern dual-plane designs; and PLLA cone threads volumise gradually rather than lift sharply. At Medisha Clinic, every lifting treatment uses Intraline 720 Dimension COG threads exclusively — and Dr Nish will advise honestly at consultation whether a thread lift, or a different treatment entirely, is right for your anatomy.
Treatment areas
Areas Treated with a PDO Thread Lift at Medisha Clinic
Dr Nish treats four key areas — each priced at £750, covering both sides of the face. Multiple areas can be combined in one session
Lower Face – Jowl Lift
The most transformative single-area treatment. Redefines the jawline, eliminates jowling, and restores a clean jaw-to-neck transition. Visible from the moment you leave the clinic.
Midface – Cheek Lift
Restores youthful cheek projection and lifts the midface, softening nasolabial folds without filler. Delivers the most natural-looking rejuvenation of any area.
Neck Lift
Tightens loose, crepey neck skin and redefines the neck-to-chin contour for a cleaner, more elegant silhouette.
Eyebrow Lift
Elevates a dropped brow tail to open the eye area, reduce upper eyelid heaviness, and restore a naturally rested, alert appearance.
2 Areas – £1,5000
Any two areas combined in a single session using 8–12 threads. Most patients choose lower face and midface, or lower face and neck.
Full Face & Neck – £1,995
Three or more areas combined using 14–18 threads. The most comprehensive non-surgical facelift available — addressing jowls, cheeks, neck, and brows simultaneously for a complete, natural-looking rejuvenation.
Suitability
Am I a Good Candidate for a PDO Thread Lift?
PDO Thread Lift works best for patients with mild to moderate facial laxity. Dr Nish will assess your skin, anatomy, and medical history in full at your consultation.
Good Candidates
- Mild to moderate sagging — jowls, cheeks, brows, or neck
- Want a visible, natural-looking lift without surgery
- Unable or unwilling to commit to surgical recovery time
- Looking to restore facial contour lost gradually over time
- Want results that improve progressively over weeks
- Considering a non-surgical facelift for the first time
May Not Be Suitable
- Severe or advanced skin laxity requiring surgical intervention
- Active skin infections or inflammation in treatment area
- Autoimmune conditions affecting skin healing
- Pregnancy or breastfeeding
- Blood-thinning medications (discuss with Dr Nish)
The best way to know is a consultation with Dr Nish. He will assess your anatomy and goals in person and give you an honest recommendation — no pressure, no obligation.
Step by step
The PDO Thread Lift Process
Every PDO Thread Lift at Medisha Clinic follows a precise, medically supervised protocol.
Medical Consultation
Dr Nish conducts a thorough face-to-face consultation, assesses your skin laxity and facial anatomy, discusses your goals, and designs a bespoke treatment plan. No treatment is performed without this step.
Pre-Treatment Preparation
The treatment area is cleansed and marked. You are asked to avoid alcohol, aspirin, ibuprofen, and blood-thinning supplements for 5–7 days prior.
Local Anaesthetic
A topical or injected local anaesthetic is administered to numb the treatment area. You may feel light pressure or tugging during insertion, but sharp pain is blocked.
Thread Insertion
Dr Nish inserts the 720 Dimension COG threads beneath the skin at precise angles using a fine needle or cannula. The barbed threads anchor in the soft tissue. Gentle tension creates the lift. The insertion process takes 20–40 minutes.
Immediate Results
The lift is immediately visible. Any excess thread is trimmed flush with the skin. Dr Nish reviews your result and provides detailed aftercare instructions. Most patients return to work within 24–48 hours.
Complimentary 4 Week Review
All patients receive a complimentary review 4 weeks after treatment. Collagen stimulation is now underway and results are becoming their best. Dr Nish assesses your result and ensures you are fully satisfied.
Transparent Pricing
PDO Thread Lift Prices – Mayfair &
Marylebone, London
Simple, transparent pricing. Every single-area treatment covers both sides of the face using 4–6 Intraline 720 Dimension COG threads. No hidden extras. No consultation fees. Every treatment performed by Dr Nish personally.
| Treatment | Areas Covered | Threads | Price |
|---|---|---|---|
| Single Area - Lower Face (Jowls) | Both sides of lower face | 4-6 | £750 |
| Single Area - Midface (Cheeks) | Both cheeks | 4-6 | £750 |
| Single Area - Neck Lift | Neck | 4-6 | £750 |
| Single Area - Eyebrow Lift | Both brows | 4-6 | £750 |
| 2 Areas | Any two areas | 8-12 | £1,500 |
| Full Face & Neck | Lower face, midface, brows & neck | 14-18 | £1,995 |
Aftercare
PDO Thread Lift Aftercare
— What to Expect
Mild swelling, bruising, and tenderness at insertion points is entirely normal for 3–7 days. Full results — particularly the collagen regeneration phase — are typically most impressive at 4–8 weeks post-treatment.
Do
- Sleep on your back for 1-2 weeks
- Keep the area clean and dry
- Apply gentle cold compress for swelling (first 24 hours)
- Take paracetamol for discomfort
- Eat soft foods if jaw area was treated (first few days)
- Attend your complimentary 4-week review
Avoid for 2 weeks
- Facials, massages or skin treatments
- Saunas, steam rooms, and hot baths
- Strenuous exercise or heavy lifting
- Sleeping on your face
- Alcohol (first 48 hours)
- Extreme or exaggerated facial movements
Clinical Evidence
What the Research Shows
PDO Thread Lift is backed by a growing body of peer-reviewed clinical evidence. Polydioxanone has been used safely in surgery for over 30 years.
Aesthetic Surgery Journal
PDO thread lifts significantly improve skin laxity and promote collagen production, with measurable improvements maintained for up to 18 months post-treatment in suitable candidates.
Dermatologic Surgery
Research demonstrated that PDO cog threads improve skin elasticity and firmness by up to 40% in treated areas, compounded by progressive collagen stimulation over the following months.
Plastic & Reconstructive Surgery
A multi-centre study reported that 95% of patients experienced improved facial contouring and skin firmness following PDO thread lift treatment, with high satisfaction at 12-month follow-up.
Why Dr Nish Shah
Award-Winning Doctor & Senior International Clinical Trainer
Dr Nish’s credentials go far beyond clinical practice. He is recognised across the UK aesthetics industry as the foremost authority on PDO thread lifting — the expert that other experts are trained by.
Clinical Training
Senior International Clinical Trainer, Derma Medical — UK’s No.1 Aesthetics Academy
Industry authority
Brand Ambassador & KOL, Intraline — global leaders in PDO thread innovation
Medical qualification
Doctor of Medicine (MD) — clinical experience in the USA and UK
Official UK Trainer
Sunekos — Diamond Innovation and Pioneering Award Winner
Training other doctors
One of a small number of UK practitioners who teaches other medical professionals to perform PDO thread lifts
location
58 South Molton Street, Mayfair W1K 5SL & Marylebone, London
Patient Reviews
What Our Patients Say
Medisha Clinic is rated 5 stars across 128 Google reviews.
“Dr Nish and his team are such lovely people and made me feel so comfortable at their clinic. Dr Nish understood my concerns and my results are so lovely. I feel so much more confident after the PDO treatment. Definitely the best clinic and would highly recommend.”
- Anna Morselli · Google Review
“I had a PDO Thread Lift with Dr Nish and I am absolutely delighted with the results. The whole process was explained thoroughly and I felt completely at ease. The lift is natural-looking and exactly what I wanted. I wouldn’t go anywhere else.”
- Sarah K. · Google Review
“Outstanding experience from consultation to results. Dr Nish is clearly an expert — he took time to understand what I wanted, was honest about what threads could achieve, and the outcome exceeded my expectations. The Mayfair clinic is beautiful too.”
- Charlotte B. · Google Review
“I’d been researching PDO thread lifts for months and chose Medisha Clinic because Dr Nish is a trainer for other doctors. That really gave me confidence. The treatment was comfortable, recovery was easy, and my jowls are genuinely lifted. Fantastic.”
- Rebecca T. · Google Review
“Dr Nish is exceptional. His knowledge of PDO threads is second to none — which makes sense given he trains other practitioners. I felt completely safe. The results at 6 weeks are incredible. Worth every penny.”
- James M. · Google Review
Frequently Asked Questions
PDO Thread Lift FAQ — Answered by Dr Nish Shah
A PDO Thread Lift is a minimally invasive, non-surgical procedure using biodegradable polydioxanone threads to physically lift and reposition sagging facial tissue. Inserted under the skin with a fine needle, the barbed threads anchor into soft tissue and create an immediate mechanical lift. As they dissolve over 6–9 months, they stimulate collagen and elastin production, producing long-term improvements in skin firmness and texture. Results from the Intraline 720 Dimension threads used at Medisha Clinic last 12–18 months. A thread face lift uses barbed COG threads to physically lift tissue; smooth mono threads are used for skin rejuvenation rather than lifting. Brow positioning — including the popular ‘fox eye’ lift — can also be addressed with threads.
At Medisha Clinic, using the Intraline 720 Dimension COG threads — clinically proven to be 4× stronger than standard threads — results last 12–18 months. Longevity depends on the area treated, number of threads, skin type, and lifestyle factors. Your complimentary 4-week review allows Dr Nish to assess your progress and advise on maintenance.
Local anaesthetic is administered before the procedure, blocking pain effectively. During treatment, patients typically feel pressure and a tugging sensation rather than sharp pain. Post-treatment, mild soreness, tenderness, and swelling at insertion points is normal for 3–7 days, easily managed with paracetamol. The vast majority of patients describe the overall experience as significantly less uncomfortable than they anticipated.
Medisha Clinic keeps pricing simple and transparent. Single area: £750 — covers both sides of the face using 4–6 Intraline 720 Dimension COG threads. Available areas: lower face (jowls), midface (cheeks), neck, and eyebrows. 2 areas: £1,500 using 8–12 threads. Full face and neck: £1,995 using 14–18 threads. A complimentary 4-week review is included. Every procedure is performed by Dr Nish Shah personally.
Most patients return to normal daily activities within 24–48 hours. Mild swelling and bruising resolves within 3–7 days. For two weeks post-treatment, avoid facials, massages, saunas, steam rooms, and strenuous exercise. Full results — including the collagen regeneration phase — become most visible at 4–8 weeks.
Intraline 720 Dimension COG threads are clinically proven to be 4× stronger than older 360-helical threads, with multi-directional barb architecture providing a stronger mechanical lift, superior tissue anchoring, and results lasting 12–18 months. Dr Nish is an official Intraline Brand Ambassador and KOL — meaning Medisha Clinic has direct access to this premium technology, unavailable at most London clinics.
PDO Thread Lift is a safe, minimally invasive procedure with an excellent clinical safety record. Polydioxanone has been used in surgical sutures for over 30 years. Common temporary side effects include mild swelling, bruising, and tenderness, resolving within 3–7 days. Rare complications such as thread visibility or asymmetry are significantly reduced by expert technique. Dr Nish discusses all risks fully during your pre-treatment consultation.
Yes. PDO Thread Lift works exceptionally well as part of a combined rejuvenation plan. Dr Nish commonly combines thread lifting with Profhilo or Sunekos for skin quality improvement, strategic dermal filler for volume, or anti-wrinkle injections. A combination approach often produces superior results to any single treatment.
Dermal fillers add volume but do not physically lift tissue. A PDO Thread Lift mechanically repositions sagging tissue and holds it in a lifted position while stimulating collagen production. For patients with jowling, loose cheeks, or neck laxity, a thread lift often produces a more accurate and longer-lasting result than filler alone. Dr Nish frequently combines both when anatomy benefits from both approaches.
In expert hands, yes — completely natural. The goal is never to make someone look “done” — it is to make them look like a refreshed, rested version of themselves. The mechanical lift repositions tissue back to where it was, rather than stretching or distorting it. Results look most natural at 4–8 weeks, once the initial swelling has fully resolved and the collagen response has refined the outcome.
Results last 12–18 months. Most patients return for a repeat treatment — which is simpler than the original as the collagen scaffolding provides a foundation.
Supporting your result with good skincare, SPF, and treatments like Profhilo or Sunekos can extend and enhance longevity. Dr Nish will advise on a personalised maintenance plan at your 4-week review.
Because when you come to Medisha Clinic, you are treated by the practitioner that other doctors in the UK are trained by. Dr Nish Shah is a Senior International Clinical Trainer for Derma Medical, Brand Ambassador and KOL for Intraline, and one of a very small number of doctors in the country who trains other medical professionals to perform this procedure. He uses exclusively the Intraline 720 Dimension COG threads — 4× stronger than standard threads. 128 five-star Google reviews. Every treatment performed by Dr Nish personally. No hidden fees. Complimentary 4-week review included as standard.
Book Your Consultation
Your Face. Lifted.
Without the Surgery.
Treated by the practitioner that other doctors in the UK are trained by. 128 five-star Google reviews. 58 South Molton Street, Mayfair, London W1K 5SL — and Marylebone.