A PDO thread lift is the non-surgical facelift that lifts on the day: dissolvable threads placed beneath the skin lift sagging tissue immediately — no surgery, no general anaesthetic. Back to work and daily life within 48 hours. At Medisha Clinic every thread lift is performed personally by Dr Nish Shah MD. He is Senior International Clinical Trainer at Derma Medical, one of the UK’s largest aesthetics training academies, where he trains other doctors to perform this procedure. He is also Brand Ambassador & Key Opinion Leader for Intraline, the manufacturer of the 720 Dimension COG threads he uses exclusively. Results last 12–18 months.
Senior International Clinical Trainer, Derma Medical — Dr Nish trains other doctors to perform this procedure
Brand Ambassador & KOL for PDO threads — exclusive access to 720 Dimension COG threads, designed for a stronger hold than standard
Every treatment performed personally by Dr Nish — over 30,000 non-surgical treatments, one of the most experienced aesthetic doctors in the UK; never delegated
Immediate, visible lift. Results lasting 12–18 months
No surgery, no general anaesthetic, back to daily life within 48 hours
From £750 per area with a complimentary 4-week review; £50 consultation redeemable against treatment
Dr Nish Shah MD · Medical Director
PDO Thread Lift Expert · Senior International Clinical Trainer · Brand Ambassador & KOL for Intraline (PDO threads) · Mayfair & Marylebone
Brand Ambassador & KOL — PDO Threads & Dermal Fillers
Ambassador and Key Opinion Leader for Intraline, manufacturer of the 720 Dimension COG threads used at Medisha — exclusive access to threads not widely available in London.
Every treatment performed personally by Dr Nish
A medically trained doctor — never delegated. Consultation, treatment and 4-week review all with Dr Nish.
Senior International Clinical Trainer — Derma Medical
One of the UK’s largest aesthetics training academies. Dr Nish teaches PDO thread lifting to other doctors.
Location
58 South Molton Street, Mayfair, London W1K 5SL · 3 min from Bond Street station, serving Mayfair and Marylebone
PDO Thread Lift
Before & After Results
Every result below was achieved at Medisha Clinic by Dr Nish Shah personally. Photographs are unedited and taken in the same lighting. Results are individual and may vary.
*Individual results may vary. All treatments performed by Dr Nish Shah MD at Medisha Clinic, Mayfair, London.
Treatment time
Starting price
Results last
Visible lift
Back to daily life
4 week review
The Treatment
What Is A PDO Thread Lift?
PDO stands for polydioxanone — a dissolvable material with a 30-year safety record in surgical stitches. In aesthetic medicine, PDO threads have been engineered to physically lift sagging facial tissue without surgery, a general anaesthetic or significant downtime.
The threads used at Medisha Clinic are COG threads, the type designed to lift. Unlike basic smooth threads, COG threads carry tiny barbs along their length. Once inserted, these barbs anchor into the tissue beneath the skin and create an immediate lift — the moment the needle is withdrawn, the face is lifted. As the threads dissolve naturally over 6–9 months, they trigger a sustained collagen and elastin response. Your skin continues to tighten and improve long after the threads have gone.
The result: an immediate, visible lift on the day, that continues to improve over the following weeks and lasts 12–18 months — with no scarring and a return to work and daily life within 48 hours.
The Technology
Why 720 Dimension Threads
— And Why It Matters
Not all PDO threads are equal. The thread technology determines the strength of the lift, how long it lasts and the collagen response. At Medisha Clinic, Dr Nish uses 720 Dimension COG threads exclusively.
- A stronger hold than standard threads. The 720° cog design is made to anchor more securely in tissue than standard 360° helical threads. Strength is a property of the thread; how long your result lasts also depends on your skin, the area and the number of threads placed./li>
- Multi-directional barb design. 720 degrees of barb coverage — anchoring from every angle for a stronger hold and a more natural result.
- Superior collagen stimulation. Greater barb surface area amplifies the body’s collagen response for long-term skin-quality improvement.
- Results lasting 12–18 months. In Dr Nish’s experience with these threads, results sit at the upper end of the usual range for PDO thread lifts.
- Available only through certified practitioners. Dr Nish’s status as Intraline Brand Ambassador and KOL gives Medisha Clinic privileged access — not widely available in London.
720 Dimension COG
vs Standard PDO Threads
720 Dimension COG
Used exclusively at Medisha Clinic
Standard PDO Threads
Used widely elsewhere
Your options compared
PDO Thread Lift vs Dermal Filler vs Skin Boosters vs Surgical Facelift
Sagging is the one concern filler cannot fix and surgery over-fixes. 4 treatments are offered for a face that has started to drop. Only one physically lifts the tissue without an operation.
PDO Thread Lift — At Medisha
- Physically lifts and repositions sagging tissue
- Immediate lift. Improves over 4–8 weeks
- Results 12–18 months with 720 Dimension threads
- Local anaesthetic. Back to daily life within 48 hours
- From £750 per area. Performed by Dr Nish
Dermal Filler
- Adds volume — does not lift tissue
- Immediate; 12–18 months
- Right for hollow cheeks, chin and jaw definition
- Reversible
- Often combined with threads. Also by Dr Nish
Skin Boosters (Profhilo / Sunekos)
- Improve skin quality, firmness and glow
- No lift and no volume
- Builds over weeks; 6–9 months
- Right for crepey, thin or dull skin
- The ideal follow-up 4 weeks after threads
Surgical Facelift
- Most dramatic lift for severe sagging
- General anaesthetic; 2–4 weeks’ recovery
- Lasts 5–10 years. Scarring
- £5,000–£15,000+
- Dr Nish will refer you if this serves you better
For mild to moderate sagging, a thread lift gives much of the visible change of surgery with none of the anaesthetic, scarring or downtime — and it can be repeated. Where volume has also been lost, Dr Nish combines threads with filler. Where skin quality is the issue, Profhilo or Sunekos follows. He will tell you honestly at consultation which of the 4 your face needs.
Treatment areas
Areas Treated with a PDO Thread Lift
at Medisha Clinic
Dr Nish treats 4 key areas — each priced at £750, covering both sides of the face. Multiple areas can be combined in one session.
Lower Face – Jowl Lift
Usually the single area with the greatest visible change. Redefines the jawline, reduces jowling and restores a clean jaw-to-neck transition. Visible from the moment you leave the clinic.
Midface – Cheek Lift
Restores youthful cheek projection and lifts the midface, softening nose-to-mouth lines without filler. A particularly natural-looking result.
Neck Lift
Tightens loose, crepey neck skin and redefines the neck-to-chin contour for a cleaner, more elegant profile.
Eyebrow Lift
Elevates a dropped brow tail to open the eye area, reduce upper-eyelid heaviness and restore a naturally rested, alert appearance.
2 Areas – £1,5000
Any 2 areas combined in a single session using 8–12 threads. Most patients choose lower face and midface, or lower face and neck.
Full Face & Neck – £1,995
3 or 4 areas combined using 14–18 threads: jowls, cheeks and neck, with the brows included if you want them. The fullest non-surgical facelift Medisha offers.
Suitability
Am I A Good Candidate
For A PDO Thread Lift?
A PDO thread lift is most effective for patients with mild to moderate sagging. Dr Nish will assess your skin, anatomy and medical history in full at your consultation.
Good Candidates
- Mild to moderate sagging — jowls, cheeks, brows or neck
- Wanting a visible, natural-looking lift without surgery
- Unable or unwilling to commit to surgical recovery time
- Looking to restore facial contour lost gradually over time
- Wanting results that improve progressively over weeks
- Considering a non-surgical facelift for the first time
May Not Be Suitable
- Severe or advanced skin sagging requiring surgery
- Active skin infection or inflammation in the treatment area
- Autoimmune conditions affecting skin healing
- Pregnancy or breastfeeding
- Blood-thinning medication (discuss with Dr Nish)
The only way to know for certain is a consultation with Dr Nish. He will assess your anatomy and goals in person and give you an honest recommendation. The consultation is £50, redeemable in full against treatment, with no obligation to proceed.
Step by step
The PDO Thread Lift Process
Every PDO thread lift at Medisha Clinic follows a precise, medically supervised protocol — the same one Dr Nish teaches to other doctors.
Medical Consultation
Dr Nish conducts a thorough face-to-face consultation, assesses your skin and facial anatomy, discusses your goals and designs a bespoke treatment plan. No treatment is performed without this step. £50, redeemable in full against treatment.
Pre-Treatment Preparation
The treatment area is cleansed and marked. You are asked to avoid alcohol, aspirin, ibuprofen and blood-thinning supplements for 5–7 days beforehand.
Local Anaesthetic
A topical or injected local anaesthetic numbs the treatment area. You may feel light pressure or tugging during insertion, but sharp pain is blocked.
Thread Insertion
Dr Nish inserts the 720 Dimension COG threads beneath the skin at precise angles using a fine needle or cannula. The barbed threads anchor in the soft tissue and gentle tension creates the lift. 20–40 minutes.
Immediate Results
The lift is immediately visible. Any excess thread is trimmed flush with the skin. Dr Nish reviews your result and provides detailed aftercare instructions. Most patients return to work within 24–48 hours.
Complimentary 4 Week Review
Collagen stimulation is under way and the result is still refining. Dr Nish assesses your result and ensures you are fully satisfied. Peak results are typically seen at 6–8 weeks.
Transparent Pricing
PDO Thread Lift Prices – Mayfair &
Marylebone, London
Simple, transparent pricing. Every single-area treatment covers both sides of the face using 4–6 720 Dimension COG threads. No hidden extras. Exact thread count confirmed at consultation. Consultation £50, redeemable in full against treatment. Every treatment performed by Dr Nish personally.
| Treatment | Areas Covered | Threads | Price |
|---|---|---|---|
| Single Area - Lower Face (Jowls) | Both sides of lower face | 4–6 × 720 Dimension COG | £750 |
| Single Area - Midface (Cheeks) | Both cheeks | 4–6 × 720 Dimension COG | £750 |
| Single Area - Neck Lift | Neck | 4–6 × 720 Dimension COG | £750 |
| Single Area - Eyebrow Lift | Both brows | 4–6 × 720 Dimension COG | £750 |
| 2 Areas | Any two areas | 8–12 threads | £1,500 |
| Full Face & Neck | Lower face, midface & neck (3 areas), with brows if wanted (4 areas) | 14–18 threads | £1,995 |
| Complimentary 4-Week Review | Every treatment | Included | Included |
| Consultation with Dr Nish | Full assessment and treatment plan | — | £50, redeemable |
Aftercare
PDO Thread Lift Aftercare
— What to Expect
Mild swelling, bruising and tenderness at the insertion points is entirely normal for 3–7 days. Any temporary dimpling smooths out within 2 weeks and a feeling of tightness settles within days. Full results — particularly the collagen phase — are typically most impressive at 6–8 weeks.
Do
- Sleep on your back for 1-2 weeks
- Keep the area clean and dry
- Apply a gentle cold compress for swelling (first 24 hours)
- Take paracetamol for discomfort
- Eat soft foods if jaw area was treated (first few days)
- Attend your complimentary 4-week review
Avoid for 2 weeks
- Facials, massages or skin treatments
- Saunas, steam rooms, and hot baths
- Strenuous exercise or heavy lifting
- Sleeping on your face
- Alcohol (first 48 hours)
- Extreme or exaggerated facial movements
Clinical Evidence
What the Research Shows
PDO thread lifting is supported by peer-reviewed clinical evidence. Polydioxanone has been used in absorbable surgical sutures since the 1980s.
Dermatologic Surgery, 2015
A review of 31 PDO cog-thread lifts found satisfactory results in around 87% of patients for both lifting and skin texture, with few and minor complications. The authors concluded PDO thread lifting is safe and effective for mild to moderate sagging. Suh et al., Dermatol Surg 2015;41(6):720–725
Journal of Cosmetic and Laser Therapy, 2018
Patients followed for 24 months after barbed PDO thread lifting showed lifting of 3–10 mm and high satisfaction, with a complication rate of about 4.8%. Ali, J Cosmet Laser Ther 2018;20(1):41–49
Dermatologic Surgery, 2017
A laboratory study of barbed PDO thread in skin measured significantly raised type 1 collagen and TGF-β1 throughout 7 months: the mechanism behind the firming that continues after the thread itself has dissolved. Kim J, Zheng Z, Kim H, Nam KA, Chung KY. Dermatol Surg 2017;43(1):74–80
Why Dr Nish Shah
Senior International Clinical Trainer & Intraline Brand Ambassador
Dr Nish’s credentials go far beyond clinical practice: he is the practitioner that other UK doctors are trained by in PDO thread lifting. “PDO thread lift is the treatment I am most passionate about — and the one I am most known for, both as a practitioner and as a trainer of other practitioners. Every patient at Medisha Clinic receives the same threads I train doctors across the UK to use, inserted with the same precision I teach.” — Dr Nish Shah MD
Clinical Training
Senior International Clinical Trainer, Derma Medical — one of the UK’s largest aesthetics training academies.
Industry Authority
Brand Ambassador & Key Opinion Leader for Intraline, manufacturer of the 720 Dimension COG threads.
Medical Qualification & Experience
Doctor of Medicine (MD) — clinical experience in the USA and the UK. Over 30,000 non-surgical treatments performed personally: one of the most experienced aesthetic doctors in the UK and London.
Official UK Trainer — Sunekos
Official UK Trainer for Sunekos, teaching its use to other practitioners.
Training Other Doctors
One of a small number of UK practitioners who teaches other medical professionals to perform PDO thread lifts.
Location
58 South Molton Street, Mayfair, London W1K 5SL, 3 minutes from Bond Street station, serving Mayfair and Marylebone · rated 5.0 on Google from 128 reviews.
Patient Reviews
What Our Patients Say
Medisha Clinic is rated 5 stars across 128 Google reviews.
“Dr Nish is one of the kindest in PDO thread lift! I had my first treatment two years ago, and I am impressed with the results and that they get even better each time. This is because of Dr Nish’s expertise, care and grace, which I experience every single time I visit the clinic.”
- Thom · Google Review
“Travelled all the way from Glasgow to have the PDO threads, and I am not disappointed! Dr Nish is so caring and gentle with his approach, and the results were fantastic as well.”
- Bedros · Google Review
“I am very happy with the care and attention I have received from Dr Nish during my appointment for PDO threads. I felt hardly any pain during the treatment, and I am absolutely stunned at how amazing the results look!”
- Helen · Google Review
“Dr Nish and his team are such lovely people and made me feel so comfortable at their clinic. Dr Nish understood my concerns and my results are so lovely. I feel so much more confident after the PDO treatment.”
- Anna Morselli · Google Review
“Dr Nish is exceptional. His knowledge of PDO threads is second to none — which makes sense given he trains other practitioners. I felt completely safe. The results at 6 weeks are incredible. Worth every penny.”
- James, Google Review
Frequently Asked Questions
PDO Thread Lift FAQ — Answered by
Dr Nish Shah
Medically written and reviewed by Dr Nish Shah MD — Medical Director, Medisha Clinic · Senior International Clinical Trainer, Derma Medical · Brand Ambassador & Key Opinion Leader for PDO Threads and Dermal Fillers · Official UK Trainer, Sunekos · Last reviewed 9 October 2026
A PDO thread lift is a minimally invasive, non-surgical procedure that uses dissolvable polydioxanone threads to physically lift and reposition sagging facial tissue. Inserted under the skin with a fine needle or cannula, the barbed threads anchor into the tissue and create an immediate lift. As they dissolve over 6–9 months, they stimulate collagen and elastin production, producing long-term improvements in skin firmness and texture. With the 720 Dimension COG threads used at Medisha Clinic, results last 12–18 months. Every treatment is performed personally by Dr Nish Shah MD, who trains other doctors to perform this procedure as Senior International Clinical Trainer at Derma Medical.
At Medisha Clinic, using 720 Dimension COG threads, designed for a stronger hold than standard threads, results last 12–18 months. The threads themselves dissolve over 6–9 months, but the collagen they stimulate continues to support and firm the skin well beyond that. Longevity depends on the area treated, the number of threads, your skin type and lifestyle factors. Your complimentary 4-week review allows Dr Nish to assess your progress and advise on maintenance.
Local anaesthetic is administered before the procedure, blocking pain effectively. During treatment, patients typically feel pressure and a tugging sensation rather than sharp pain. Afterwards, mild soreness, tenderness and swelling at the insertion points is normal for 3–7 days and is easily managed with paracetamol. The vast majority of patients describe the overall experience as significantly less uncomfortable than they anticipated.
Medisha Clinic keeps pricing simple and transparent. A single area is £750 and covers both sides of the face using 4–6 720 Dimension COG threads. Available areas are the lower face (jowls), midface (cheeks), neck and eyebrows. 2 areas are £1,500 using 8–12 threads, and the full face and neck is £1,995 using 14–18 threads: 3 or 4 areas, with the brow optional. A complimentary 4-week review is included. Consultation with Dr Nish is £50, redeemable in full against treatment. Every procedure is performed by Dr Nish Shah personally. The clinic is at 58 South Molton Street, Mayfair, London W1K 5SL, 3 minutes from Bond Street station.
Most patients return to daily activities within 24–48 hours. Mild swelling and bruising resolve within 3–7 days, and any temporary dimpling smooths out within 2 weeks. For 2 weeks after treatment, avoid facials, massages, saunas, steam rooms and strenuous exercise, and sleep on your back. Full results — including the collagen phase — become most visible at 6–8 weeks.
720 Dimension COG threads are designed for a stronger hold than standard 360° helical threads. Their multi-directional barb design — barbs through a full 720 degrees — gives a stronger lift, superior anchoring in the tissue and results lasting 12–18 months. Dr Nish is Brand Ambassador and KOL for Intraline, the manufacturer of these threads. That gives Medisha Clinic direct access to a technology not widely available in London.
A PDO thread lift is a safe, minimally invasive procedure with an excellent clinical safety record. Polydioxanone has been used in surgical stitches for over 30 years. Common, temporary effects are mild swelling at the insertion points (3–7 days), bruising (5–10 days), tenderness, temporary dimpling (within 2 weeks) and a feeling of tightness (settles within days). Uncommon effects, rare with expert technique, include a thread that can be seen or felt under the skin, asymmetry requiring adjustment, thread migration, infection, and nerve sensitivity at insertion sites. The risk of complications falls significantly when a doctor with advanced anatomy knowledge and specific PDO thread training performs the procedure. As a Senior International Clinical Trainer, Dr Nish teaches other medical professionals the techniques that minimise risk. All risks are discussed fully at your consultation.
Yes — a PDO thread lift works exceptionally well as part of a combined rejuvenation plan. Dr Nish commonly combines thread lifting with Profhilo or Sunekos for skin quality, strategic dermal filler for volume, or anti-wrinkle injections for expression lines. Threads and filler can be done on the same day or staged apart — which is right for you is decided at your consultation. A combination approach often produces superior results to any single treatment.
Dermal fillers add volume but do not physically lift tissue. A PDO thread lift mechanically repositions sagging tissue and holds it in a lifted position while stimulating collagen production. For patients with jowling, loose cheeks or neck sagging, a thread lift often produces a more accurate and longer-lasting result than filler alone. Dr Nish frequently combines both when the anatomy benefits from both approaches.
In expert hands, yes: natural-looking. The goal is never to make someone look ‘done’. It is to make them look like a refreshed, rested version of themselves. The lift repositions tissue back to where it was, rather than stretching or distorting it. Results look most natural at 6–8 weeks, once the initial swelling has fully resolved and the collagen response has refined the outcome.
If you have mild to moderate sagging and want a natural, refreshed result without surgery, a PDO thread lift is an excellent choice. There is no general anaesthetic, you are back to work and daily life within 24–48 hours, the result is immediate, it lasts 12–18 months, and it starts from £750. A surgical facelift gives a more dramatic result for severe sagging and lasts 5–10 years. It requires a general anaesthetic and 2–4 weeks of recovery, carries scarring and surgical risk, and typically costs £5,000–£15,000 or more. If you have significant skin excess or severe sagging, Dr Nish will tell you honestly that surgery may serve you better and refer you accordingly. He will never perform a thread lift on a patient who would be better served by a different treatment.
Because when you come to Medisha Clinic, you are treated by the practitioner that other doctors in the UK are trained by. Dr Nish Shah MD is a Senior International Clinical Trainer at Derma Medical and Brand Ambassador and KOL for Intraline, the manufacturer of the 720 Dimension COG threads. He is one of a very small number of doctors in the country who trains other medical professionals to perform this procedure. He uses exclusively 720 Dimension COG threads, designed for a stronger hold than standard threads. Rated 5.0 on Google from 128 reviews. Every treatment performed by Dr Nish personally. No hidden fees, a complimentary 4-week review as standard, and a £50 consultation redeemable against treatment. 58 South Molton Street, Mayfair, London W1K 5SL, serving Mayfair and Marylebone.
Book Your Consultation
Your Face. Lifted.
Without the Surgery.
Treated by the practitioner that other doctors in the UK are trained by. Rated 5.0 on Google from 128 reviews. From £750 per area with your 4-week review included. 58 South Molton Street, Mayfair, London W1K 5SL. One clinic, serving Mayfair and Marylebone.